Skip Ribbon Commands
Skip to main content
Dr. Hussnain A Janjua
Associate Professor
Industrial Biotechnology

ASAB
National University of Sciences and Technology (NUST)
Campus H-12, Islamabad
Tel : +92-51-9085-6149

Specialization
Microbes as biocatalysts and biofuel cells, genomics and proteomics of pathogenic and environmental microorganisms, metabolic engineering and synthetic microbiology for bioactive microbial metabolites, biosynthesis of silver nanoparticles         

Education
PhD (2005): Imperial Collage London, United Kingdom, Post Doctoral Research Fellow (2005-2007): IMBM, UWC, Cape Town, South Africa. Post Doctoral Research Fellow (2007-2011): CIBIO, UNITN, Italy

Dr. Hussnain A Janjua earned his doctoral degree in Microbial Molecular Biology in 2005 from the Imperial College London under the supervision of Professor David Leak. His work focused on Molecular Genetics of Xanthobacter autotrophicus Py2. After completing his PhD, he was given a consultancy position in the same lab. Later in 2005, he was awarded Postdoctoral Research Fellowship and moved to “Institute for Microbial Biotechnology and Metagenomics” (IMBM) at the University of Western Cape in Cape Town, South Africa where he worked with Professor Don Cowan on Fungal solubilisation of low rank coal into chemical commodities of industrial applications. In 2007 he managed to win research funding from Provincia Autonoma di Trento, Italy for a project titled ‘Genome Plasticity of P. aeruginosa: from comparative genomics to virulence’. He joined Laboratory of Microbial Genomics at the Centre for Integrative Biology (CIBIO), Universita Degli Studi Di Trento where he worked with Dr Olivier Jousson as a Post Doctoral Research Fellow, till June 2011 on host-pathogen interactions, genotyping and comparative genomics of P. aeruginosa clinical isolates. In September 2011 Dr Janjua joined Quaid-i-Azam University as HEC Foreign Professor where he was among the founding faculty members of the Department of Pharmacy. Dr Janjua has also spent few months at Syed Babar Ali School of Science and Engineering (LUMS) where he was involved in developing Microbiology, Virology and Biochemistry courses he was also involved in research projects focused on the antimicrobial applications of different types of silver nanomaterials. Dr Janjua is serving ASAB, NUST since September 2012, he is actively involved in industrial biotechnology research, he is supervising 4 MSc and 3 Ph.D. students. He has also developed Industrial Biotechnology, Gene Therapy and Modern Research Techniques courses at the postgraduate and undergraduate level.​​
 
RESEARCH SEMINARS/INVITED TALKS

Hussnain A Janjua and David J. Leak Molecular Genetic studies of alkene metabolism in X. autotrophicus Py2. Oral presentation Annual Departmental Seminars for PhD students at the Department of Biological Sciences Imperial College London 7th May 2003.

Hussnain A Janjua, M. Estela Silva-Stenico, Caryn J. Vengadajellum, Stephanie G. Burton, Sue T. L. Harrison and Don A. Cowan. Biotransformation of low rank coal by novel microbial strains. Oral presentation at SAS BMB XXth conference (3rd to 6th July 2006) Pietermaritzburg campus of the University of KwaZulu-Natal South Africa.

Hussnain A Janjua, M. Estela Silva-Stenico, Caryn J. Vengadajellum, Stephanie G. Burton, Sue T. L. Harrison and Don A. Cowan. Biodegradation of low rank coal by various fungal isolates, identification of extracellular fungal proteins using proteomics approach that are involved in coal degradation. Oral presentation at CIBIO University of Trento, Trento Italy (January 2008).  .

Hussnain A Janjua. Future Perspectives of Advanced Biofuels. Oral presentation at International Workshop on Sustainable Energy and Membrane Systems for Desalination and Water Reuse, 10-11 December 2013, National University of Sciences and Technology (NUST), Islamabad, Pakistan.

Hussnain A Janjua. Microbiology and Industrial Applications. Oral Presentation at Seminar in Youth Summit 2014. Expo Centre, 1-A Johar Town Lahore-Pakistan.

Hussnain A Janjua. Recent advances in characterization of microbial biofuel cell-factories. Oral Presentation in ICB-2014. 1st International Conference on Bio Energy 2014 “Challenges and opportunities in Pakistan” November 20-21, 2014.

Hussnian A Janjua. Nanotechnology and Microbial Genomics. Oral Presentation on 6th workshop “Impact of Bioinformatics in life sciences May” 9th 2015.

Hussnain A Janjua. Nanoparticles as Potential Therapeutic Targets to cure Bacterial Infections. Oral Presentation in 2nd International Conference on Biotechnology “Challenges and opportunities in Pakistan” February 24-25, 2016.

Hussnain A Janjua. Synthetic Biology; Origin, Scope and Applications. AIOU Lecture Symposium on Frontiers in Biology; From Discovery to Applications. January 19th 2017.

Hussnain A Janjua. From Therapeutic to Therapeutic Agents; An Integrated Nanobiology and Systems Biology Approach. Oral Presentation in 3rd International Conference on Biotechnology 2017. February 8th -9th 2017.

Hussnain A Janjua. Integrated Systematic Approaches Towards Rational Treatment of Bacterial Infection in an Era of Escalating/Increasing/Progressive Antibiotic Resistance. Oral Presentation in Regional Conference to Promote Safe and Secure Science in the Middle East, South and Southeast Asia – Kuala Lumpur, Malaysia – Feb 5-9, 2018.

Hussnain A Janjua. Green Synthesis of nanomaterials and their biomedical applications. Oral Presentation in ICONN SCME NUST, Islamabad, Pakistan- 2018 November 1-2

INTERNATIONAL COURSES

2007 CPGR course: Proteomics University of Cape Town (IIDMM), Cape Town South Africa (June 12th –June 14th 2007).
2008 3S Biology Summer School in Bio-Informatics, CIBIO, UNITN, Trento, Italy (August 21st -August 25th 2008).
2011 Crash Course Research Funding and intellectual Property, University of Trento, Trento, Italy (April 19thMay 30th 2011).

RESEARCH GRANTS

1- Research Grant (worth 135000 €) won from Provincia Autonoma di Trento, Italy for Post-Doctoral Research at CIBIO, UNITN, Trento, Italy “Genome plasticity in pseudomonas aeruginosa: from comparative genomics to virulence”.

2- Research Grant (worth 1.97 Million Pakistani Rupees) won as Co-PI from Higher Education Commission, Islamabad, Pakistan “Pangenome analysis of indigenous multi-drug resistant Staphylococcus aureus strains and reverse vaccinology approaches to identify potential novel therapeutics”.

3- Research Grant (worth 6.41 Million Pakistani Rupees) won as Co-PI from Higher Education Commission, Islamabad Pakistan “Intrinsic benign antifouling functional polymers and transparent compositions for laboratory scale photo-bioreactors”.

4- Research Grant (worth 12.66 Million Pakistani Rupees) won as Co-PI from Higher Education Commission, Islamabad Pakistan “Water treatment using high performance antifouling functional polymer membranes in combination with activated carbon filtration”.

5- Research Grant (worth 6.1 Million Pakistani Rupees) won as P.I from Higher Education Commission, Islamabad, Pakistan “Discovery and validation of circulating protein biomarker panels for diagnosing hepatocellular carcinoma”.
 

Corresponding author*


1-  Khan F, Akhtar N, Jalal Nasir, Szemigielski R, Hayat QM, Ahmad HB, Yangi M, Janjua HA*:Carbon dot wrapped ZnO nanoparticles-based photochemical sensor for selective monitoring of H2O2 release. Microchimica Acta 2019, 126: 127-135.

2 -  Ikram A, Zaheer T, Awan FM, Obaid A, Naz A, Hanif R, Paracha RZ, Ali A, Naveed AK, Janjua HA*: Exploring NS3/4A, NS5A and NS5B proteins to design conserved subunit multi-epitope vaccine against HCV utilizing immunoinformatics approach. Scientific Reports-Nature 2018, 8: 16107.

3 -  Bhatti HT, Ahmad N, Niazi MBK, Alvi MAR, Anwar MN, Cheema W, Tariq S, Batool M, Aman Z, Janjua HA, Khan AL, Khan A, Ahmad N. Graphene Oxide-PES, based mixed matrix membranes for controllable antibacterial activity against Salmonella Typhi and water treatment. Accepted in International Journal of Polymer Sciences 2018, Article ID 7842148, 12 pages.

4 -  Khalid M, Johonson E, Vij A, Bouwer A, Janjua HA*, Betenbaugh MJ. Anaerobic digestion restricted to Phase I for nutrient release and energy production using waste water grown Chlorella vulgaris. Journal of Chemical Engineering 2018, 352: 756-764.

5 -  Naveed M, Imran K, Mushtaq A, Mumtaz AS, Janjua HA, Khalid N. Insilico functional and tumour suppressor role of hypothetical protein PCNXL2 with regulation of the Notch Signalling Pathway. RSC Advances 2018, 8: 21414.

6 -  Younus A, Munawar S, Bhatti MF, Ikram A, Awan FM, Jabeen I, Virk N, Janjua HA, Arshad M. Structure function mutation analysis and prediction of the potential impact of high risk non-synonymous  single nucleotide polymorphism on Poliovirus 2A protease stability using comprehensive proteomics approach. MDPI-Genes 2018, 9(5): 228. 

7 -  Awan FM, Obaid A, Naz A, Ali A, Ahmad J, Naveed AK, Janjua HA*: MicroRNA pharmacogenmoics based integrated model of miR-17-92 cluster in sorafenib resistant hepatocellular carcinoma (HCC) cells reveals a strategy to forestall drug resistance. Scientific Reports-Nature 2017, 7: 11448.

8 -  Hashmi MU, Khan F, Khalid N, Shahid AA, Javed A, Alam T, Jalal N, Hayat MQ, Abbas S R, Janjua HA*: Hydrogels incorporated with silver nanocolloids prepared from antioxidant rich Aerva javanica as disruptive agents against burn wound infections. J Colloids and Surf A 2017, 529: 475-486.

9 -  Bibi Z, Ahmad J, Siddiqa A, Paracha RZ, Saeed T, Ali A, Janjua HA, Ullah S, Abdallah EB, Roux O. Formal Modeling of mTOR associated biological regulatory network reveals novel therapeutic strategy for the treatment of cancer. Frontiers in Physiology 2017, 8: 416.

10 -  Khalid M, Khalid N, Ahmed I, Janjua HA*: Comparative studies of three novel freshwater microalgae strains for synthesis of silver nanoparticles: Insights of formulation, characterization and biological activities. Journal of Applied Phycology 2017, 29: 1851–1863.

11 -  Arif S, Batool A, Khalid N, Ahmed I, Janjua HA*: Comparative analysis of stability and biological activities of violacein and starch capped silver nanoparticles. RSC Advances 2017, 7(8): 4468-4478.

12 -  Awan FM, Obaid A, Ikram A, Janjua HA*: Mutation-Structure-Function Relationship Based Integrated Strategy Reveals the Potential Impact of Deleterious Missense Mutations in Autophagy Related Proteins on Hepatocellular Carcinoma (HCC): A Comprehensive Informatics Approach. International Journal of Molecular Sciences 2017, 18(1): 139.

13 -  Ikram A, Obaid A, Awan FM, Hanif R, Naz A, Paracha RZ, Ali A, Janjua HA*: Identification of drug resistance and immune-driven variations in hepatitis C virus (HCV) NS3/4A, NS5A and NS5B regions reveals a new approach toward personalized medicine. Antiviral Res 2017, 137: 112-124.

14 -  Hassan A, Naz A, Obaid A, Paracha RZ, Naz K, Awan FM, Muhmmad SA, Janjua HA, Ahmad J, Ali A: Pangenome and immuno-proteomics analysis of Acinetobacter baumannii strains revealed the core peptide vaccine targets. BMC Genomics 2016, 17(1):732.

15 -  Khan F, Hashmi MU, Khalid N, Hayat MQ, Ikram A, Janjua HA*: Controlled assembly of silver nano-fluid in Heliotropium crispum extract: A potent anti-biofilm and bactericidal formulation. Applied Surface Science 2016, 387: 317-331.

16 -  Bibi Z, Ahmad J, Ali A, Siddiqa A, Shahzad S, Tareen SH, Janjua HA, Khusro S: On the modeling and analysis of the biological regulatory network of NF-{\ kappa} B activation in HIV-1 infection. Complex Adaptive Systems Modeling 2016, 4(1): 1.

17 -  Awan FM, Naz A, Obaid A, Ali A, Ahmad J, Anjum S, Janjua HA*: Identification of Circulating Biomarker Candidates for Hepatocellular Carcinoma (HCC): An Integrated Prioritization Approach. PLoS One 2015 10 (9):e0138913.

18 -  Ashraf S, Chatha MA, Ejaz W, Janjua HA, Hussain I: Lysozyme-coated silver nanoparticles for differentiating bacterial strains on the basis of antibacterial activity. Nanoscale Res Lett 2014, 9(1):565.

19 -  Awan FM, Anjum S, Obaid A, Ali A, Paracha RZ, Janjua HA*: In-silico analysis of claudin-5 reveals novel putative sites for post-translational modifications: Insights into potential molecular determinants of blood-brain barrier breach during HIV-1 infiltration. Infect Genet Evol 2014, 27:355-365.

20 -  Janjua HA, Segata N, Bernabo P, Tamburini S, Ellen A, Jousson O: Clinical populations of Pseudomonas aeruginosa isolated from acute infections show a wide virulence range partially correlated with population structure and virulence gene expression. Microbiology 2012, 158(8):2089-2098.

21 -  Fumanelli L, Iannelli M, Janjua HA, Jousson O: Mathematical modeling of bacterial virulence and host–pathogen interactions in the Dictyostelium/Pseudomonas system. Journal of theoretical biology 2011, 270(1):19-24.

22 -  Silva-Stenico ME, Vengadajellum CJ, Janjua HA, Harrison ST, Burton SG, Cowan DA: Degradation of low rank coal by Trichoderma atroviride ES11. Journal of industrial microbiology & biotechnology 2007, 34(9):625-631.
 
 

Industrial Biotechnology (PG)

Modern Research Techniques (UG)

Gene Therapy and Viral Vectors (UG)