Muhammad Faraz Bhatti received his PhD degree in Molecular Biology from Imperial College London, UK. Currently he is serving as an Associate Professor and Director Local Quality Enhancement Cell (DLQEC) at Atta-ur-Rahman School of Applied Biosciences (ASAB), National University of Sciences & Technology (NUST).
Fungal viruses (mycoviruses) ubiquitously infect all major taxa of fungi. Knowledge of mycovirusesis relatively new and that most scientists are hardly aware of its existence. The role of mycoviruses in their respective hosts is largely unknown. There is need for extensive research in the field of Mycology and Virology to elucidate the role of emerging mycoviruses in different fungi.
FARAZ AND HIS RESEARCH TEAM ARE CURRENTLY INTERESTED IN:
- Identification of novel mycoviruses infecting pathogenic fungi
- Molecular characterisation of novel mycoviruses and understanding its phylogeny
- Studying the impact of mycoviruses on the fitness of their hosts
- Mycovirus induced gene silencing
- Extending the host range of mycoviruses using novel techniques
- Exploitation of mycoviruses for biological control
LIST OF GRANTS SECURED
APPROVED RESEARCH GRANTS AS PRINCIPAL INVESTIGATOR (PI)
1. Identification of mycoviral infections in various pathogenic Aspergillus species found in Pakistan (Start-up research grant sponsored by Higher Education Commission (HEC) of Pakistan (0.5 Million Rupees; Completed)
2. Identification and characterization of mycoviruses invading Botrytis species to exploit their potential as a biocontrol agent. National research program for universities (NRPU) sponsored by Higher Education Commission of Pakistan (5.9 Million PKR; in progress)
APPROVED RESEARCH GRANTS AS CO-PI
1. Identification and transcriptional profiling of Arabidopsis thaliana and Tomato Mitogen Activated Protein Kinases against biotic and abiotic stress”.(Start-up research grant sponsored by Higher Education Commission (HEC) of Pakistan (0.5 Million Rupees; Completed)
HONORS AND AWARDS
1. Bursary awarded by Wellcome Genome Campus to attend an Advance course on Fungal Pathogen Genomics at Hinxton, Cambridge, UK(13-18 May, 2018)
2. Best poster award in conference on promoting safe and secure science organized by Academy of Sciences Malaysia and National Academy of Sciences, USA) 2018
3. Travel award to attend conference in Malaysia sponsored by NASEM (USA) and ASM (Malaysia (2018)
4. Best Community Service Teacher Award (2016-17)
5. Best Teacher Award (2015-16)
6. Best Community Service Teacher Award (2014-15)
7. High Achiever’s Award (2014-15)
RESEARCH SUPERVISION OF STUDENTS
Supervision of MS
||Muhammad Azam Fareed
Co-supervision of MS
||Syed Muhammad Hamza Banoori
||Haris Ahmad Khan
1- Bhatti, M. F., Bignell, E. M. and Coutts, R. H. A., (2011). Complete nucleotide sequences of two dsRNAs associated with a new partitivirus infecting Aspergillus fumigatus. Arch. Virol., 156, 1677-1680.
2- Bhatti, M. F., Jamal, A., Petrou, M. A, Cairns, T. C., Bignell, E. M. and Coutts, R.H.A., (2011). The effects of dsRNA mycoviruses on growth and murine virulence of Aspergillus fumigatus. Fungal Genet. Biol., 48, 1071-1075.
3- Bhatti, M. F., Jamal, A., Bignell, E. M., Petrou, M. A. and Coutts, R.H.A., (2012). Incidence of dsRNA mycoviruses in a collection of Aspergillus fumigatus isolates. Mycopathologia, 174, 323-326.
4- Kozlakidis, Z., Herrero, N., Ozkan, S., Kanhayuwa, L., Jamal, A., Bhatti, M. F. and Coutts, R. H. A., (2013). Sequence determination of a quadripartite dsRNA virus isolated from Aspergillus foetidus. Arch. Virol., 158, 267-72.
5- Kozlakidis, Z., Herrero, N., Ozkan, S., Kanhayuwa, L., Bhatti, M. F. and Coutts, R. H. A., (2013). A novel dsRNA element isolated from the Aspergillus foetidus mycovirus complex. Arch. Virol., 158, 2625-2628.
6- Siddiqa, A., Zainab, M., Qadri, I., Bhatti, M. F. and Parish, J. L., (2014). Prevalence and genotyping of high risk human papillomavirus in cervical cancer samples from Punjab, Pakistan. Viruses, 6, 2762-2777
7- Siddiqa, A., Léon,K. C., James, C. D., Bhatti, M. F., Roberts, S. and Parish, J. L. (2015).
The human papillomavirus type 16 L1 protein interacts directly with E2 and enhances E2-dependent replication and transcription activation
J. Gen. Virol.97; 2274-2285.
8- Siddiqa, A. and Bhatti, M. F. (2016) Genetic variation of high-risk HPV-16 from a cervical cancer biopsy collected in Pakistan. Future Virol. 11; 31-38.
9- Iftikhar, H., Naveed, N., Virk, N., Bhatti, M.F. and Song, F., (2017). In silico analysis reveals widespread presence of three gene families, MAPK, MAPKK and MAPKKK, of the MAPK cascade from crop plants of Solanaceae in comparison to the distantly-related syntenic species from Rubiaceae, coffee. PeerJ, 5, p.e3255.
10- Jan, S. U., Jamil, M., Alipour, H., Bhatti, M. F., and Gul, A. (2017). Analysis of salinity tolerance potential in synthetic hexaploid wheat. Pakistan Journal of Botany, 49(4); 1269-1278.
11- Aslam, R., Williams, L.E., Bhatti, M.F. and Virk, N. (2017). Genome-wide analysis of wheat calcium ATPases and potential role of selected ACA s and ECA s in calcium stress. BMC Plant Biology, 17(1); p.174.
12- Younus, A. and Bhatti M.F. (2017) A Comprehensive Computational Mutation-Structure Function Approach for Determining Potential Drug Target Sites among Poliovirus 2A Protease. Tropical Journal of Pharmaceutical Research, 16(12); 2831-2841.
13- Asif, A., Zeeshan, M., Hashmi, I., Zahid, U. and Bhatti. M. F. (2018). Microbial quality assessment of indoor air in a large hospital building during winter and spring seasons. Build Environ., 135; 68-73.
14- Younus, A., Munawar, S., Bhatti, M. F., Ikram, A., Awan, F., Jabeen, I., Virk, N., Janjua, H., Arshad, M., (2018). Structure-Function Mutational Analysis and Prediction of the Potential Impact of High Risk Non-Synonymous Single-Nucleotide Polymorphism on Poliovirus 2A Protease Stability Using Comprehensive Informatics Approaches. Genes 9; 228.
15- Fahim, A., Rehman, Z., Bhatti, M. F., Ali, A., Virk, N., Rashid, A., Paracha, R. Z. (2018) Structural insights and characterization of human Npas4 protein. PeerJ 6:e4978
16- Iftikhar, H., Virk, N., Bhatti, M.F. (2018). Homology Modeling of CTR1 Protein Kinase Domain in Solanaceae Species for Identification of Salient Features in terms of Structure and Function, and Interaction Analysis with Lipids. Current Proteomics, 15(4); 329-340.
17- Tabriz, A., Alvi, M.A.U.R., Niazi, M.B.K., Batool, M., Bhatti, M.F., Khan, A.L., Khan, A.U., Jamil, T. and Ahmad, N.M., (2018). Quaternized Trimethyl Functionalized Chitosan Based Antifungal Membranes for Drinking Water Treatment. Carbohydrate Polymers. 207; 17-25.
18- Hanif, J., Khalid, N., Khan, R.S., Bhatti, M.F., Hayat, M.Q., Ismail, M., Andleeb, S., Mansoor, Q., Khan, F., Amin, F. and Hanif, R., Hashmi M, M., U. Janjua, H. A., (2019). Formulation of active packaging system using Artemisia scoparia for enhancing shelf life of fresh fruits. Materials Science and Engineering: C. 100; 82-93.
Other International Journals
1- Ghafoor, B., Ali, M.N., Ansari, U., Bhatti, M.F., Mir, M., Akhtar, H. and Darakhshan, F., (2016). New Biofunctional Loading of Natural Antimicrobial Agent in Biodegradable Polymeric Films for Biomedical Applications. International Journal of Biomaterials, 2016.
2- Younus, A., Bhatti, M.F., Ahmad, T., Virk, N., Arshad, M., Janjua, H.A., (2016). Protein structure modelling, ligand docking and active site analysis of mutated Poliovirus 2a protease gene isolated from the blood of Pakistani polio infected patients. International Journal of Advances in Science Engineering and Technology. 4(3), Spl. Issue 2, 52-57.
3- Iftikhar, H., Virk, N., Cheng, X., Bhatti, M.F., (2016). In silico analysis reveals multiple genes of mapk, mapkk and mapkkk gene families of the mapk cascade in Nicotiana tabacum. International Journal of Advances in Science Engineering and Technology, 4(3), Spl. Issue 2, 42-47
Publication in HEC recognized National Journals
1- Ali, M. A., Bhatti, M. F., Abbas, A. and Khan, I. A., (2010). Assessment of Inheritance of Some Multigenic Characters in Cotton (Gossypium hirsutum). J. Agric. Res., 48, 25-33.
1- Ghori, Z., Iftikhar, H., Bhatti, M.F., Sharma, I., Kazi, A.G. and Ahmad, P., (2015). Phytoextraction: the use of plants to remove heavy metals from soil. In Plant Metal Interaction (pp. 385-409).
1- Aslam, R., Farthing, E.C., Virk, N., Bhatti, M.F., Williams, L.E. (2016) Stress Induces the Retention of Introns in ECA3 Transcripts in Wheat. 4th International Conference on Advances in Agricultural, Biological & Ecological Sciences (AABES-16) Dec. 1-2, 2016 London(UK)
2- Shamsi, W., Jamal, A., Virk, N., Bhatti, M. F. (2018). The Mycovirus Database; An E Bank for Mycoviral Genomes. 2nd ICRMR; 2018,7-11
• Molecular Biology
• Plant Physiology
• Community Service Learning Course
• Fungal Biology
• Techniques in Plant Molecular Biology
• Advance Plant Physiology